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About Peptide Mapping

Creative Biolabs has established a platform to analyze the peptide map of therapeutic drug candidates, strictly following the ICH Topic Q6b guideline. Utilizing suitable enzymes or chemicals, selective fragmentation of the product is digested into discrete peptides. The resulting peptide fragments are identified by HPLC and other appropriate analytical procedure. The peptide fragments are determined utilizing techniques such as N-terminal sequencing, amino acid compositional analysis, and mass spectrometry. Validated peptide mapping is frequently an appropriate approach to confirm the structure/identity of the desired therapeutic product for lot release purposes.

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